Physician’s Profile

Adam D. Griesemer, MD

Director, Large Animal Xenotransplantation Laboratory, Columbia Center for Translational Immunology
Affiliations: 
NewYork-Presbyterian/Columbia
Komansky Center for Children's Health
NewYork-Presbyterian/Morgan Stanley Children's Hospital
NewYork-Presbyterian/Weill Cornell
Contact Phone: 
(212) 305-9691
Board Certificates: 
Surgery
Expertise: 
Transplant Surgery
Pediatric Transplant Surgery
Portal Hypertension
Surgery
Minimally Invasive Surgery
Shunts
Living Donor Liver Surgery
Abdominal Organ Transplant, Pediatric
Abdominal Organ Transplantation
Liver Transplant
Liver Transplant, Pediatric
Living Donor Transplantation
Organ Transplant, Pediatric
Transplantation Surgery
Honors: 

Faculty Development Grant, American Society of Transplant Surgeons, 2018

Nominated for Physician of the Year by Surgical Intensive Care Unit, 2017

AASLD Career Development Award in Liver Transplantation, 2015

Forde Award for Research, Columbia University, 2013

Department of Surgery's Chairman's Research Award, Columbia University College of Physicians and Surgeons, 2013

Louis V. Gerstner, Jr. Scholar – Research Award, Columbia University College of Physicians and Surgeons, 2013

Blakemore Prize - Best Resident Research Award, Columbia University College of Physicians and Surgeons, 2011

Blakemore Award - Best Resident Research Award, Columbia University College of Physicians and Surgeons, 2009

American Society of Transplantation Young Investigator Award, Transplantation Biology Research Center, Harvard Medical School, 2008

International Xenotransplantation Travel Grant, Transplantation Biology Research Center, Harvard Medical School, 2007

American Society of Transplantation/JDRF Research Fellowship Award, Transplantation Biology Research Center, Harvard Medical School, 2005

Alpha Omega Alpha, University of Missouri-Columbia School of Medicine, 2003

Marion DeWeese Award for Excellence in General Surgery, University of Missouri-Columbia School of Medicine, 2003

Donald Silver Award for Excellence in Vascular Surgery, University of Missouri-Columbia School of Medicine, 2003

Interests: 
Use of Tregs to control natural antibody responses and facilitate xenogeneic bone marrow engraftment
Xenogeneic tolerance induction via mixed chimerism and thymus transplant
Allogeneic tolerance induction
Control of humoral rejection
Small for Size Syndrome after Living Donor Liver Transplantation
Lab Members: 
Paula Alonso-Guallart, DVM, PhD Candidate
Sulemon Chaudry, MD, Former Lab Member
Jeffery Stern, MD, Former Lab Member
Joshua Weiner, MD, Former Lab Member
Karl Erik Berglund, MD, Postdoctoral Research Fellow
Nathaly Llore, MD, Postdoctoral Research Fellow
Publications: 
Chaudhry SG, Bentley-Hibbert S, Stern J, Lobritto S, Martinez M, Vittorio J, Halazun KJ, Lee HT, Emond J, Kato T, Samstein B, Griesemer A. Growth of Liver Allografts Over Time in Pediatric Transplant Recipients. Pediatric Transplantation. 2018 Mar;22(2). PMID: 29334158 Elnaggar AS, Griesemer AD, Bentley-Hibbert S, Brown RS, Martinez M, Lobritto SJ, Kato T, Emond JC. Liver Atrophy and Regeneration in Non-Cirrhotic Portal Vein Thrombosis: Effect of Surgical Shunts. Liver Transplantation. 2018. In Press.  PMID: 29377486 Quillin RC, Bongu A, Kasper v, Vittorio JM, Martinez M, Lobritto SJ, Griesemer AD, Guarrera JG. Roux-en-Y enterolith leading to obstruction and ischemic necrosis after pediatric orthoscopic liver transplantation. Pediatric Transplantation. 2018. In Press. Przybyszewski EM, Verna EC, Lobritto SJ, Martinez M, Vittorio J, Fox AN, Samstein B, Kato T, Griesemer AD, Emond JC. Durable Clinical and Immunologic Advantage of Living Donor Liver Transplantation in Children. Transplantation2018. In Press. PMID: 29369249 Vallabhajosyula P, Hirakata A, Weiss M, Griesemer A, Shimizu A, Hong H, Habertheuer A, Tchipashvili V, Yamada K, Sachs DH. Effect of the Diabetic State on Islet Engraftment and Function in a Large Animal Model of Islet-Kidney Transplantation. Cell Transplant. 2017 Nov;26(11):1755-1762. PMID: 29338381 Rahnemai-Azar AA, Griesemer AD, Velasco ML, Kato T. Ex vivo excision of retroperitoneal soft tissue tumors: A case report. Oncol Lett. 2017 Oct;14(4):4863-4865. PMID: 29085493 Kato Y, Griesemer AD, Wu A, Sondermeijer H, Weiner JI, Duran-Struuck R, Martinez M, Slate A, Romanov A, Lefkowitch JH, Sykes M, and Kato T. Novel H-Shunt Venovenous Bypass for Liver Transplantation in Cynomolgus Macaques. Comparative Medicine. 2017 Oct 1;67(5):436-441. PMID: 28935006 Halazun KJ, Rana AA, Fortune B, Quillan RC, Verna EC, Samstein B, Guarrera JV, Kato T, Griesemer AD, Fox A, Brown RS Jr, Emond JC. No Country for Old Livers? Examining and Optimizing the Utilization of Elderly Liver Grafts. Am J Transplant. 2017 Sep 27.  PMID: 28960723 Carpenter DJ, Granot T, Matsuoka N, Senda T, Kumar BV, Thome JJC, Gordon CL, Miron M, Weiner J, Connors T, Lerner H, Friedman A, Kato T, Griesemer AD,Farber DL. Human immunology studies using organ donors: impact of clinical variations on immune parameters in tissues and circulation. Am J Transplant. 2017 Jul 18. PMID: 28719147 Halazun KJ, Quillin RC, Rosenblatt R, Bongu A, Griesemer AD, Kato T, Smith C, Michelassi F, Guarrera JV, Samstein B, Brown RS Jr, Emond JC. Expanding the Margins: High Volume Utilization of Marginal Liver Grafts Among >2000 Liver Transplants at a Single Institution. Ann Surg. 2017 Jun 27. PMID: 28657945. Griesemer AD, Emond JC. Big improvements for the smallest recipients. Liver Transpl. 2017 Jun 15. PMID: 28618184. Granot T, Senda T, Carpenter DJ, Matsuoka N, Weiner J, Gordon CL, Miron M, Kumar B, Griesemer A, Ho S, Lerner H, Thome J, Connors T, Reizis B, Farber DL. Dendritic cells display subset and tissue-specific maturation dynamics over human life. Immunity. 2017 Mar 21;46(3):504-515.  Duran-Struuck R, Sondermeijer HP, Bühler L, Alonso-Guallart P, Zitsman J, Kato Y, Wu A, McMurchy AN, Woodland D, Griesemer A, Martinez M, Boskovic S, Kawai T, Cosimi AB, Wuu CS, Slate A, Mapara M, Baker S, Tokarz R, Dʼ Agati V, Hammer S, Pereira M, Lipkin WI, Wekerle T, Levings M, Sykes M. Effect of ex vivo Expanded Recipient Regulatory T Cells on Hematopoietic Chimerism and Kidney Allograft Tolerance Across MHC Barriers in Cynomolgus Macaques. Transplantation. 2017 Eeb;101(2):274-283. PMID: 27846155 Halazun KJ, Najjar M, Abdelmessih RM, Samstein B, Griesemer AD, Guarrera JV, Kato T, Verna EC, Emond JC, Brown RS Jr. Recurrence After Liver Transplantation for Hepatocellular Carcinoma: A New MORAL to the Story. Ann Surg. 2016 Sep 16. PMID: 27611615 Emond JC, Griesemer AD.Tolerance in clinical liver transplantation: The long road ahead. Hepatology2017 Feb;65(2):411-413.  PMID: 27718261 Zuber J, Shonts B, Lau S, Obradovic A, Fu J, Yang S, Lambert M, Coley S, Weiner J, Thome J, DeWolf S, Farber DL, Shen Y, Caillat-Zucman S, Bhagat G, Griesemer A, Martinez M, Kato T, Sykes M. Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome. Science Immunology. 2016 October 07; 1(4). Halazun KJ, Przybyszewski EM, Griesemer AD, Cherqui D, Michelassi F, Guarrera JV, Kato T, Brown RS Jr, Emond JC, Samstein B. Leaning to the Left: Increasing the Donor Pool by Using the Left Lobe, Outcomes of the Largest Single-center North American Experience of Left Lobe Adult-to-adult Living Donor Liver Transplantation. Ann Surg. 2016 Jul 18. PMID: 27433896 Martinez M, Brodlie S, Griesemer A, Kato T, Harren P, Gordon B, Parker T, Levine D, Tyberg T, Starc T,