The purpose of this study is to test an investigational device called the Echopulse for treatment of breast fibroadenomas in women. Fibroadenomas are benign (noncancerous) breast tumors. These lumps can occur alone, in groups, or as a complex of lumps together. Sometimes women feel these in the breast when doing regular self-breast exams, or they may be found during a routine mammogram. Some are small (less than an inch in size), and others are quite large (the size of a lemon or larger).Several symptoms could be associated to the presence of fibroadenoma.

By studying healthy mastectomy specimens, we hope to delineate breast ductal anatomy  and gain a better understanding of ductal layout.

By studying mastectomy specimens with DCIS, we hope to delineate breast ductal anatomy, gain a better understanding of ductal layout, and fundamentally impact management and treatment of breast disease.

The Mammaprint study is a genetic study among Chinese women with breast cancer. The purpose of this study is to identify molecular factors or biomarkers that may be used to assess risk for breast cancer in this population. Identification of such markers could facilitate better risk assessment, detection methods, as well as development of better-targeted therapies. 

In this study, patients first undergo surgery to remove their breast cancer. Samples of their tissue are then sent for genetic analysis, and DNA testing is performed on blood samples. 

The primary goal is to determine whether retrieval of a solitary papilloma can be performed endoscopically by ductoscopy including very thin basket to avoid open surgical excision. Secondary aim will be to evaluate the therapeutic success of this procedure.

To evaluate the ability of radiofrequency ablation (RFA) of breast cancer lumpectomy sites to extend the final negative margin and decrease the rates of reoperation.

This is a prospective study that will assess the impact of MammaPrint on chemotherapy + endocrine versus endocrine alone treatment decisions in patients with an Oncotype Intermediate Score.

The aim of this study is to understand if racial disparities in breast cancer prognosis can in part be explained by differences in insulin resistance and insulin signaling between black and white women. 

This study aims to determine the feasibility of assessing microRNA profiles in nipple aspirate fluid (NAF), serum, and tissue of women diagnosed with DCIS or invasive breast cancer. Because 90% of breast cancers originate from ductal epithelium, it is possible that cells and secretions collected from such ducts would allow for earlier detection of breast cancer. Ideally, NAF may be used to identify biomarkers that predict the risk of breast cancer and/or detect breast cancer in its early stages.