A2ALL Deux

A2ALL: Adult-to-Adult Living Donor Transplant Cohort Study

The study is being conducted for the following reasons:

  1. To determine the prevalence, course, and predictors of poor Health Related Quality of Life (HRQOL) outcomes associated with living donor donation.
  2. To collect data and biosamples prior to, during, and after a living donor liver transplant (LDLT) among all donors and recipients for use by other adult-to-adult living donor liver transplant studies and future studies.
  3. To study the effects of pressure and flow on the outcomes of LDLT.
  4. To characterize the differences between living donor liver transplant and deceased donor liver transplant in terms of recipient post-transplant outcomes including patient and graft survival, surgical morbidity, and resource utilization.
  5. To compare the long-term histological outcomes in recipients of LDLT and deceased donor liver transplant (DDLT) with recurrent hepatitis C virus (HCV) infection.
  6. To understand the history of pain management and to measure quality of care in pain control in living donors following partial hepatectomy.

Trial Website: https://clinicaltrials.gov/show/NCT01619475

Are you Eligible? (Inclusion Criteria)

Inclusion Criteria:

  1. Age 18 or older at the time of consent
  2. Has had a living donor identified and accepted and LDLT is planned
  3. Informed consent obtained
  4. Is listed for single organ (liver) transplantation
  1. Age 18 or older at the time of consent
  2. Has undergone donor evaluation process and was accepted and donation surgery is planned
  3. Informed consent obtained

Exclusion Criteria:


Specialty Area(s)


Trial Location

New York, NY 10032
United States