A Phase II Perioperative Combination Study With Chemotherapy and Immunotherapy For Locoregional Gastric or GE Junction Adenocarcinoma.
A Phase II Study of Chemotherapy and Immune Checkpoint Blockade With Pembrolizumab in the Perioperative and Maintenance Treatment of Locoregional Gastric or GE Junction Adenocarcinoma
This study is done to determine and evaluate the efficacy of combination therapy with immune checkpoint blockade and chemotherapy used in the perioperative period in eradicating micrometastatic disease. Additionally, the study compares paired tissue and serum samples (pre-treatment and post-treatment) from individually treated patients to explore the immune effects of combination therapy and predictors of response.
Are you Eligible? (Inclusion Criteria)
Patients must be have gastric/GE juncrtion adenocarcinoma and have never done surgery before treatment.